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rs454886

From SNPedia

Orientationminus
Stabilizedminus
Make rs454886(C;C)
Make rs454886(C;T)
Make rs454886(T;T)
ReferenceGRCh38 38.1/142
Chromosome5
Position112810420
GeneAPC
is asnp
is mentioned by
dbSNPrs454886
ClinGenrs454886
ebirs454886
HLIrs454886
Exacrs454886
Varsomers454886
Maprs454886
PheGenIrs454886
hapmaprs454886
1000 genomesrs454886
hgdprs454886
ensemblrs454886
gopubmedrs454886
geneviewrs454886
scholarrs454886
googlers454886
pharmgkbrs454886
gwascentralrs454886
openSNPrs454886
23andMers454886
23andMe allrs454886
SNP Nexus

SNPshotrs454886
SNPdbers454886
MSV3drs454886
GWAS Ctlgrs454886
GMAF0.3655
Max Magnitude
? (C;C) (C;T) (T;T) 28
[PMID 18708403OA-icon.png] 798 invasive breast cancer cases and 843 unaffected controls
  • rs454886 per allele odds ratio, 1.23; 95% confidence intervals, 1.05-1.43; P(trend) = 0.01


OMIM114500
Desc
Variant
Relatedalso


ClinVar
Risk rs454886(C;C)
Alt rs454886(C;C)
Reference rs454886(T;T)
Significance Other
Disease Familial colorectal cancer
Variation info
Gene APC
CLNDBN Familial colorectal cancer
Reversed 1
HGVS NC_000005.9:g.112146117A>G
CLNSRC ClinVar
CLNACC RCV000074069.1,



GET Evidence
rs454886
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.289062
summary