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rs4613763

From SNPedia

Orientationplus
Stabilizedplus
Make rs4613763(C;C)
Make rs4613763(C;T)
Make rs4613763(T;T)
ReferenceGRCh38 38.1/141
Chromosome5
Position40392626
is asnp
is mentioned by
dbSNPrs4613763
ebirs4613763
HLIrs4613763
Exacrs4613763
Varsomers4613763
Maprs4613763
PheGenIrs4613763
hapmaprs4613763
1000 genomesrs4613763
hgdprs4613763
ensemblrs4613763
gopubmedrs4613763
geneviewrs4613763
scholarrs4613763
googlers4613763
pharmgkbrs4613763
gwascentralrs4613763
openSNPrs4613763
23andMers4613763
23andMe allrs4613763
SNP Nexus

SNPshotrs4613763
SNPdbers4613763
MSV3drs4613763
GWAS Ctlgrs4613763
GMAF0.1097
Max Magnitude
? (C;C) (C;T) (T;T) 28
rs4613763 increases susceptibility to Crohn's disease 1.56 times for carriers of the C allele [PMID 17447842OA-icon.png]
Neighborrs2371685
Distance502
Neighborrs10512734
Distance877
GWAS snp
PMID [PMID 18587394OA-icon.png]
Trait Crohn's disease
Title Genome-wide assocation defines more than 30 distinct susceptibility loci for Crohn's disease
Risk Allele C
P-val 7.0000000000000003E-27
Odds Ratio 1.32 [NR]
OMIM612261
DescINFLAMMATORY BOWEL DISEASE 17; IBD17
Variant
Relatedalso
OMIM612262
DescINFLAMMATORY BOWEL DISEASE 18; IBD18
Variant
Relatedalso


[PMID 20222910] Susceptibility loci reported in genome-wide association studies are associated with Crohn's disease in Canadian children


[PMID 17068223OA-icon.png] A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.


[PMID 20018022OA-icon.png] Replication of recently identified associated single-nucleotide polymorphisms from six autoimmune diseases in Genetic Analysis Workshop 16 rheumatoid arthritis data.


[PMID 21304977OA-icon.png] An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.


GET Evidence
rs4613763
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.148438
summary



GWAS snp
PMID [PMID 21833088OA-icon.png]
Trait Multiple sclerosis
Title Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Risk Allele G
P-val 3E-16
Odds Ratio 1.20 [1.18-1.22]