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rs4639966

From SNPedia

Orientationplus
Stabilizedplus
Make rs4639966(C;C)
Make rs4639966(C;T)
Make rs4639966(T;T)
ReferenceGRCh38 38.1/141
Chromosome11
Position118702810
is asnp
is mentioned by
dbSNPrs4639966
ebirs4639966
HLIrs4639966
Exacrs4639966
Varsomers4639966
Maprs4639966
PheGenIrs4639966
hapmaprs4639966
1000 genomesrs4639966
hgdprs4639966
ensemblrs4639966
gopubmedrs4639966
geneviewrs4639966
scholarrs4639966
googlers4639966
pharmgkbrs4639966
gwascentralrs4639966
openSNPrs4639966
23andMers4639966
23andMe allrs4639966
SNP Nexus

SNPshotrs4639966
SNPdbers4639966
MSV3drs4639966
GWAS Ctlgrs4639966
GMAF0.2603
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 19838193]
Trait Systemic lupus erythematosus
Title Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
Risk Allele G
P-val 1E-16
Odds Ratio 1.29 [1.22-1.37]


GET Evidence
rs4639966
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.242188
summary



[PMID 23002088] A single-nucleotide polymorphism rs4639966 in 11q23.3 is associated with clinical features of systemic lupus erythematosus in the Chinese population.


[PMID 24001599] Three SNPs in chromosome 11q23.3 are independently associated with systemic lupus erythematosus in Asians


[PMID 25862617] Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations