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rs4654748

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 2 2.90 ng/mL lower Vitamin B6 blood concentration
(C;T) 2 1.45 ng/mL lower Vitamin B6 blood concentration
(T;T) 0 normal Vitamin B6 blood concentration
ReferenceGRCh38 38.1/141
Chromosome1
Position21459575
GeneNBPF3
is asnp
is mentioned by
dbSNPrs4654748
ebirs4654748
HLIrs4654748
Exacrs4654748
Varsomers4654748
Maprs4654748
PheGenIrs4654748
hapmaprs4654748
1000 genomesrs4654748
hgdprs4654748
ensemblrs4654748
gopubmedrs4654748
geneviewrs4654748
scholarrs4654748
googlers4654748
pharmgkbrs4654748
gwascentralrs4654748
openSNPrs4654748
23andMers4654748
23andMe allrs4654748
SNP Nexus

SNPshotrs4654748
SNPdbers4654748
MSV3drs4654748
GWAS Ctlgrs4654748
GMAF0.4141
Max Magnitude2
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 19303062OA-icon.png]
Trait Folate pathway vitamins
Title Genome-wide Association Study of Vitamin B6, Vitamin B12, Folate, and Homocysteine Blood Concentrations
Risk Allele C
P-val 8E-18
Odds Ratio 1.45 [0.90-2.00] ng/ml decrease



OMIM612957
Desc
Variant
Relatedalso

This is one of the SNPs reported by NutraHacker.

[PMID 21115529OA-icon.png] Genetics and genomics of human aging.


GET Evidence
rs4654748
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.335938
summary



GWAS snp
PMID [PMID 19744961OA-icon.png]
Trait Folate pathway vitamin levels
Title Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.
Risk Allele
P-val 4E-11
Odds Ratio .10 [0.080-0.120] unit decrease