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rs4657139

From SNPedia

Orientationplus
Stabilizedplus
Make rs4657139(A;A)
Make rs4657139(A;T)
Make rs4657139(T;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position162060117
is asnp
is mentioned by
dbSNPrs4657139
ebirs4657139
HLIrs4657139
Exacrs4657139
Varsomers4657139
Maprs4657139
PheGenIrs4657139
hapmaprs4657139
1000 genomesrs4657139
hgdprs4657139
ensemblrs4657139
gopubmedrs4657139
geneviewrs4657139
scholarrs4657139
googlers4657139
pharmgkbrs4657139
gwascentralrs4657139
openSNPrs4657139
23andMers4657139
23andMe allrs4657139
SNP Nexus

SNPshotrs4657139
SNPdbers4657139
MSV3drs4657139
GWAS Ctlgrs4657139
GMAF0.4059
Max Magnitude
? (A;A) (A;T) (T;T) 28
[PMID 19204306OA-icon.png] rs10494366, rs4657139 and rs16847548 were significantly associated with adjusted QT interval in whites. relative hazard of SCD associated with each C allele at rs16847548 was 1.31. rs12567209 was also independently associated with SCD in whites (relative hazard 0.57, 95% confidence interval 0.39 to 0.83, P=0.003). No significant associations observed in blacks.


[PMID 20215044OA-icon.png] Relationship of Common Candidate Gene Variants to Electrocardiographic T-Wave Peak to T-Wave End Interval and T-Wave Morphology Parameters


[PMID 20538168] Polymorphisms in the NOS1AP Gene Modulate QT Interval Duration and Risk of Arrhythmias in the Long QT Syndrome


[PMID 19019189OA-icon.png] Common candidate gene variants are associated with QT interval duration in the general population.


[PMID 19180230OA-icon.png] Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population.


[PMID 19822806OA-icon.png] NOS1AP is a genetic modifier of the long-QT syndrome.


[PMID 22708720] Identification of a novel KCNQ1 mutation in a large Saudi family with long QT syndrome: clinical consequences and preventive implications.