rs4665058

plus

Geno	Mag	Summary
(A;A)	2.1	~4x increased risk among Europeans for sudden cardiac death
(A;C)	2	2x increased risk among Europeans for sudden cardiac death
(C;C)	0	common in complete genomics

Reference

GRCh38 38.1/141

Chromosome

2

Position

159333698

Gene

BAZ2B

is a	snp
is	mentioned by
dbSNP	rs4665058
dbSNP (classic)	rs4665058
ClinGen	rs4665058
ebi	rs4665058
HLI	rs4665058
Exac	rs4665058
Gnomad	rs4665058
Varsome	rs4665058
LitVar	rs4665058
Map	rs4665058
PheGenI	rs4665058
Biobank	rs4665058
1000 genomes	rs4665058
hgdp	rs4665058
ensembl	rs4665058
geneview	rs4665058
scholar	rs4665058
google	rs4665058
pharmgkb	rs4665058
gwascentral	rs4665058
openSNP	rs4665058
23andMe	rs4665058
SNPshot	rs4665058
SNPdbe	rs4665058
MSV3d	rs4665058
GWAS Ctlg	rs4665058

GMAF

0.1111

Max Magnitude

2.1

?

(A;A) (A;C) (C;C)

28

rs4665058 is a SNP in the bromodomain adjacent zinc finger domain 2B BAZ2B locus on ch 2q24.2.

A GWAS meta-analysis in 1,283 cases of sudden cardiac death (SCD; presumably from myocardial infarction) and >20,000 control individuals of European ancestry from 5 studies, with follow-up genotyping in 3,000+ cases, associated rs4665058 with SCD risk (p = 1.8×10e?10). The per allele odds ratio for the risk allele, rs4665058(A), is 1.92 (CI: 1.57–2.34).10.1371/journal.pgen.1002158

GWAS snp
PMID	[PMID 21738491 ]
Trait
Title	Identification of a Sudden Cardiac Death Susceptibility Locus at 2q24.2 through Genome-Wide Association in European Ancestry Individuals.
Risk Allele	A
P-val	2E-10
Odds Ratio	1.9200 [1.57-2.34]