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rs4689388

From SNPedia

Orientationplus
Stabilizedplus
Make rs4689388(A;A)
Make rs4689388(A;G)
Make rs4689388(G;G)
ReferenceGRCh38 38.1/141
Chromosome4
Position6268329
GeneWFS1
is asnp
is mentioned by
dbSNPrs4689388
ebirs4689388
HLIrs4689388
Exacrs4689388
Varsomers4689388
Maprs4689388
PheGenIrs4689388
hapmaprs4689388
1000 genomesrs4689388
hgdprs4689388
ensemblrs4689388
gopubmedrs4689388
geneviewrs4689388
scholarrs4689388
googlers4689388
pharmgkbrs4689388
gwascentralrs4689388
openSNPrs4689388
23andMers4689388
23andMe allrs4689388
SNP Nexus

SNPshotrs4689388
SNPdbers4689388
MSV3drs4689388
GWAS Ctlgrs4689388
GMAF0.2594
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19734900]
Trait Type 2 diabetes and other traits
Title Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
Risk Allele T
P-val 1E-8
Odds Ratio 1.16 [1.10-1.21]


[PMID 18678618OA-icon.png] Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes.


GET Evidence
rs4689388
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.710938
summary



[PMID 25800097] Differential promoter activity by nucleotide substitution at a type 2 diabetes GWAS signal upstream of wolframin gene


[PMID 27377286] Multicapillary gel electrophoresis based analysis of genetic variants in the WFS1 gene.