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rs4763655

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) >1.10x risk
(A;G) 1.10x risk
(G;G) 0 common
ReferenceGRCh38 38.1/141
Chromosome12
Position9602982
GeneKLRB1
is asnp
is mentioned by
dbSNPrs4763655
ebirs4763655
HLIrs4763655
Exacrs4763655
Varsomers4763655
Maprs4763655
PheGenIrs4763655
hapmaprs4763655
1000 genomesrs4763655
hgdprs4763655
ensemblrs4763655
gopubmedrs4763655
geneviewrs4763655
scholarrs4763655
googlers4763655
pharmgkbrs4763655
gwascentralrs4763655
openSNPrs4763655
23andMers4763655
23andMe allrs4763655
SNP Nexus

SNPshotrs4763655
SNPdbers4763655
MSV3drs4763655
GWAS Ctlgrs4763655
GMAF0.343
Max Magnitude0
? (A;A) (A;G) (G;G) 28
rs4763655 has been reported in a large study to be associated with multiple sclerosis.

The risk allele (oriented to the dbSNP entry) is (A); the odds ratio associated with this allele is 1.10 (CI 1.04-1.17). [PMID 17660530]



[PMID 21610746OA-icon.png] Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655


GET Evidence
rs4763655
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.328125
summary



[PMID 22492128] Association of SNPs rs6498169 and rs10984447 with multiple sclerosis in Saudi patients: a model of the usefulness of familial aggregates in identifying genetic linkage in a multifactorial disease.