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rs4806660

From SNPedia

Orientationplus
Stabilizedplus
Make rs4806660(C;C)
Make rs4806660(C;T)
Make rs4806660(T;T)
ReferenceGRCh38 38.1/141
Chromosome19
Position55313266
GeneTMEM150B
is asnp
is mentioned by
dbSNPrs4806660
ebirs4806660
HLIrs4806660
Exacrs4806660
Varsomers4806660
Maprs4806660
PheGenIrs4806660
hapmaprs4806660
1000 genomesrs4806660
hgdprs4806660
ensemblrs4806660
gopubmedrs4806660
geneviewrs4806660
scholarrs4806660
googlers4806660
pharmgkbrs4806660
gwascentralrs4806660
openSNPrs4806660
23andMers4806660
23andMe allrs4806660
SNP Nexus

SNPshotrs4806660
SNPdbers4806660
MSV3drs4806660
GWAS Ctlgrs4806660
GMAF0.2961
Max Magnitude
? (C;C) (C;T) (T;T) 28
rs4806660 is a SNP on chromosome 19.

A case control study of ~2,000 women found that each rs4806660(C) allele was associated with an average decrease in age at menopause of ~1 month. This also meant that each rs4806660(T) allele yielded an odds ratio of 1.45 (CI: 1.32–1.59, p = 8.88 x 10e-16) of not having early menopause, defined as occurring before the age of 46.[PMID 20952801OA-icon.png]

Overall, women homozygous for the "early" alleles at all 4 SNPs found in this study were ~4 times more likely to undergo menopause early compared to women who had a total of 3 or less risk alleles. However, the ability to predict which women will actually undergo early menopause using these 4 SNPs is still low.[PMID 20952801OA-icon.png]

OMIM612884
Desc
Variant
Relatedalso