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rs4833095

From SNPedia

Orientationplus
Stabilizedplus
Make rs4833095(C;C)
Make rs4833095(C;T)
Make rs4833095(T;T)
ReferenceGRCh38 38.1/141
Chromosome4
Position38798089
GeneTLR1
is asnp
is mentioned by
dbSNPrs4833095
ebirs4833095
HLIrs4833095
Exacrs4833095
Varsomers4833095
Maprs4833095
PheGenIrs4833095
hapmaprs4833095
1000 genomesrs4833095
hgdprs4833095
ensemblrs4833095
gopubmedrs4833095
geneviewrs4833095
scholarrs4833095
googlers4833095
pharmgkbrs4833095
gwascentralrs4833095
openSNPrs4833095
23andMers4833095
23andMe allrs4833095
SNP Nexus

SNPshotrs4833095
SNPdbers4833095
MSV3drs4833095
GWAS Ctlgrs4833095
GMAF0.4711
Max Magnitude
? (C;C) (C;T) (T;T) 28
OMIM601194
Desc
Variant0002
Relatedalso

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[PMID 18396467OA-icon.png] Genetic variation and haplotype structures of innate immunity genes in eastern India.


[PMID 18635889OA-icon.png] Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis.


[PMID 18752252] Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk.


[PMID 19134200OA-icon.png] No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis.


[PMID 19503599OA-icon.png] The impact of divergence time on the nature of population structure: an example from Iceland.


[PMID 19543401OA-icon.png] Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.


[PMID 19567509OA-icon.png] Genetic variants and prostate cancer risk: candidate replication and exploration of viral restriction genes.


[PMID 20200442OA-icon.png] Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.


[PMID 20459687OA-icon.png] Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring.


[PMID 20478407] The toll-like receptor 1 variant S248N influences placental malaria.


[PMID 20617178OA-icon.png] Leprosy and the adaptation of human toll-like receptor 1.


[PMID 21108742] Toll-like receptor 1 gene polymorphisms in childhood IgA nephropathy: a case-control study in the Korean population.


[PMID 21872627] Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.


GET Evidence
TLR1-N248S
aa_change Asn248Ser
aa_change_short N248S
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.434176
summary



[PMID 23478521OA-icon.png] Toll-Like Receptor 1 Polymorphisms and Associated Outcomes in Sepsis After Traumatic Injury: A Candidate Gene Association Study


ClinVar
Risk rs4833095(C;C)
Alt rs4833095(C;C)
Reference rs4833095(T;T)
Significance Other
Disease Leprosy 5
Variation info
Gene TLR1
CLNDBN Leprosy 5
Reversed 0
HGVS NC_000004.11:g.38799710T>C
CLNSRC OMIM Allelic Variant
CLNACC RCV000008866.2,



[PMID 23255565OA-icon.png] Racial variation in toll-like receptor variants among women with pelvic inflammatory disease.


[PMID 25028161] Polymorphisms in TLR1, TLR6 and TLR10 genes and the risk of Graves' disease

GWAS snp
PMID [PMID 24388013OA-icon.png]
Trait Asthma and hay fever
Title Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
Risk Allele T
P-val 5E-12
Odds Ratio 1.20 [1.14-1.26]


[PMID 25687912] Toll-like receptor 1 and 10 polymorphisms, Helicobacter pylori susceptibility and risk of gastric lesions in a high-risk Chinese population


[PMID 24780078] Association between TLR1 polymorphisms and alopecia areata