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rs4833103

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Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) normal
(A;C) 0.75x decreased risk for Non-hodgkin's lymphoma
(C;C) 0.74x decreased risk for Non-hodgkin's lymphoma
ReferenceGRCh38 38.1/141
Chromosome4
Position38813881
is asnp
is mentioned by
dbSNPrs4833103
ebirs4833103
HLIrs4833103
Exacrs4833103
Varsomers4833103
Maprs4833103
PheGenIrs4833103
hapmaprs4833103
1000 genomesrs4833103
hgdprs4833103
ensemblrs4833103
gopubmedrs4833103
geneviewrs4833103
scholarrs4833103
googlers4833103
pharmgkbrs4833103
gwascentralrs4833103
openSNPrs4833103
23andMers4833103
23andMe allrs4833103
SNP Nexus

SNPshotrs4833103
SNPdbers4833103
MSV3drs4833103
GWAS Ctlgrs4833103
GMAF0.2319
Max Magnitude
? (A;A) (A;C) (C;C) 28
rs4833103 is a SNP located in a cluster of toll-like receptor genes.

In a pooled analysis including three population-based case-control studies of Non-Hodgkin's lymphoma (1,946 cases, 1,808 controls), two SNPs in moderate linkage disequilibrium were significantly associated with NHL: rs10008492 (odds ratio for (C;T) genotype 1.12, CI: 0.97-1.30; OR(T;T) 1.40, CI: 1.15-1.71; p(trend)=0.001) and rs4833103 (OR(A;C) 0.75, CI: 0.64-0.88; OR(A;A) 0.74, CI: 0.62-0.90; p(trend)=0.002; p(dominant)=0.0002).[PMID 19029192OA-icon.png]


[PMID 19307593OA-icon.png] Signals of recent positive selection in a worldwide sample of human populations.


[PMID 20200442OA-icon.png] Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.


[PMID 21872627] Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.


[PMID 23815888OA-icon.png] Inference of human continental origin and admixture proportions using a highly discriminative ancestry informative 41-SNP panel.