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rs4886605

From SNPedia

Orientationplus
Stabilizedplus
Make rs4886605(C;C)
Make rs4886605(C;T)
Make rs4886605(T;T)
ReferenceGRCh38 38.1/141
Chromosome15
Position74733647
is asnp
is mentioned by
dbSNPrs4886605
ebirs4886605
HLIrs4886605
Exacrs4886605
Varsomers4886605
Maprs4886605
PheGenIrs4886605
hapmaprs4886605
1000 genomesrs4886605
hgdprs4886605
ensemblrs4886605
gopubmedrs4886605
geneviewrs4886605
scholarrs4886605
googlers4886605
pharmgkbrs4886605
gwascentralrs4886605
openSNPrs4886605
23andMers4886605
23andMe allrs4886605
SNP Nexus

SNPshotrs4886605
SNPdbers4886605
MSV3drs4886605
GWAS Ctlgrs4886605
GMAF0.3939
Max Magnitude
? (C;C) (C;T) (T;T) 28
[PMID 18415690] 577 testicular germ cell tumors cases (254 seminoma, 323 nonseminoma) and 707 controls.

inversely associated with nonseminoma:

  • rs4886605 OR = 0.75 (95% CI = 0.54-1.04) among the heterozygotes and OR = 0.37, 95% CI = 0.12-1.11 among the homozygotes with a p-value for trend = 0.02;
  • rs2606345 OR = 0.69 (95% CI = 0.51-0.93) among heterozygotes and OR = 0.70 (95% CI = 0.42-1.17) among homozygotes, with a p-value for trend = 0.02.

[PMID 19110417] hepatocellular carcinoma in Chinese populations

  • increased risk rs4646421 (OR 1.30, 95% CI 1.05-1.61)
  • increased risk rs2198843 (OR 1.33, 95% CI 1.05-1.69)
  • reduced risk rs4886605 (OR 0.70. 95% CI 0.52-0.94)


[PMID 25189712OA-icon.png] The association between CYP1A1 genetic polymorphisms and coronary artery disease in the Uygur and Han of China