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rs4894

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 normal
(A;C) 1.78x increased risk for schizophrenia in males
(C;C) 1.78x increased risk for schizophrenia in males
ReferenceGRCh38 38.1/141
Chromosome22
Position39521510
GeneATF4
is asnp
is mentioned by
dbSNPrs4894
ebirs4894
HLIrs4894
Exacrs4894
Varsomers4894
Maprs4894
PheGenIrs4894
hapmaprs4894
1000 genomesrs4894
hgdprs4894
ensemblrs4894
gopubmedrs4894
geneviewrs4894
scholarrs4894
googlers4894
pharmgkbrs4894
gwascentralrs4894
openSNPrs4894
23andMers4894
23andMe allrs4894
SNP Nexus

SNPshotrs4894
SNPdbers4894
MSV3drs4894
GWAS Ctlgrs4894
GMAF0.2534
Max Magnitude0
? (A;A) (A;C) (C;C) 28

This SNP is on its own, as well as part of a specific haplotype, associated with an overall higher risk for schizophrenia in males based on a study of 352 Chinese patients (186 males). The reported odds ratio is 1.78 (CI: 1.19-2.67, p=0.004). [PMID 18163433]

Neighborrs17001266
Distance885


GET Evidence
ATF4-Q22P
aa_change Gln22Pro
aa_change_short Q22P
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.302844
summary