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rs489693

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in clinvar
Make rs489693(A;A)
Make rs489693(A;C)
ReferenceGRCh38 38.1/141
Chromosome18
Position60215554
is asnp
is mentioned by
dbSNPrs489693
ebirs489693
HLIrs489693
Exacrs489693
Varsomers489693
Maprs489693
PheGenIrs489693
hapmaprs489693
1000 genomesrs489693
hgdprs489693
ensemblrs489693
gopubmedrs489693
geneviewrs489693
scholarrs489693
googlers489693
pharmgkbrs489693
gwascentralrs489693
openSNPrs489693
23andMers489693
23andMe allrs489693
SNP Nexus

SNPshotrs489693
SNPdbers489693
MSV3drs489693
GWAS Ctlgrs489693
GMAF0.326
Max Magnitude0
? (A;A) (A;C) (C;C) 28
GWAS snp
PMID [PMID 19557197OA-icon.png]
Trait Waist circumference
Title NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE Consortium
Risk Allele
P-val 4E-7
Odds Ratio NR NR


[PMID 22566560OA-icon.png] Association Between Common Variants Near the Melanocortin 4 Receptor Gene and Severe Antipsychotic Drug-Induced Weight Gain.

GET Evidence
rs489693
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.367188
summary



ClinVar
Risk rs489693(A;A)
Alt rs489693(A;A)
Reference rs489693(C;C)
Significance Drug-response
Disease risperidone response - Toxicity/ADR ziprasidone response - Toxicity/ADR paliperidone response - Toxicity/ADR clozapine response - Toxicity/ADR haloperidol response - Toxicity/ADR amisulpride response - Toxicity/ADR quetiapine response - Toxicity/ADR aripiprazole response - Toxicity/ADR olanzapine response - Toxicity/ADR
Variation info
Gene
CLNDBN risperidone response - Toxicity/ADR ziprasidone response - Toxicity/ADR paliperidone response - Toxicity/ADR clozapine response - Toxicity/ADR haloperidol response - Toxicity/ADR amisulpride response - Toxicity/ADR quetiapine response - Toxicity/ADR aripiprazole response - Toxicity/ADR olanzapine response - Toxicity/ADR
Reversed 0
HGVS NC_000018.9:g.57882787C>A
CLNSRC PharmGKB Clinical Annotation PharmGKB
CLNACC RCV000211159.1, RCV000211203.1, RCV000211214.1, RCV000211221.1, RCV000211305.1, RCV000211314.1, RCV000211337.1, RCV000211401.1, RCV000211428.1,