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rs495828

From SNPedia

Orientationplus
Stabilizedplus
Make rs495828(G;G)
Make rs495828(G;T)
Make rs495828(T;T)
ReferenceGRCh38 38.1/141
Chromosome9
Position133279294
is asnp
is mentioned by
dbSNPrs495828
ebirs495828
HLIrs495828
Exacrs495828
Varsomers495828
Maprs495828
PheGenIrs495828
hapmaprs495828
1000 genomesrs495828
hgdprs495828
ensemblrs495828
gopubmedrs495828
geneviewrs495828
scholarrs495828
googlers495828
pharmgkbrs495828
gwascentralrs495828
openSNPrs495828
23andMers495828
23andMe allrs495828
SNP Nexus

SNPshotrs495828
SNPdbers495828
MSV3drs495828
GWAS Ctlgrs495828
GMAF0.1887
Max Magnitude
? (G;G) (G;T) (T;T) 28
GWAS snp
PMID [PMID 22672568OA-icon.png]
Trait Venous thromboembolism
Title A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q.
Risk Allele T
P-val 3E-16
Odds Ratio 1.6500 None
GWAS snp
PMID [PMID 20139978]
Trait Hematological and biochemical traits
Title Genome-wide association study of hematological and biochemical traits in a Japanese population
Risk Allele T
P-val 6E-10
Odds Ratio 0.26 [NR] % variance
GWAS snp
PMID [PMID 20066004]
Trait Angiotensin-converting enzyme activity
Title A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor
Risk Allele A
P-val 3E-8
Odds Ratio 4.90 [NR] % variance


[PMID 24803075] Influence of ABO genotype and phenotype on angiotensin-converting enzyme plasma activity

[PMID 23816557OA-icon.png] Re-evaluation of ABO gene polymorphisms detected in a genome-wide association study and risk of pancreatic ductal adenocarcinoma in a Chinese population.

[PMID 23202125OA-icon.png] Large-scale association analysis identifies new risk loci for coronary artery disease.

[PMID 22258027] A common variant of the ABO gene protects against hypertension in a Spanish population.

[PMID 21832968] Pharmacogenetic predictors of angiotensin-converting enzyme inhibitor-induced cough: the role of ACE, ABO, and BDKRB2 genes.

[PMID 19729612OA-icon.png] Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-selectin.

[PMID 19648918OA-icon.png] Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer.


GET Evidence
rs495828
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.140625
summary



GWAS snp
PMID [PMID 24816252OA-icon.png]
Trait Blood metabolite ratios
Title An atlas of genetic influences on human blood metabolites.
Risk Allele T
P-val 6E-34
Odds Ratio .09 [0.074-0.102] unit decrease