Have questions? Visit https://www.reddit.com/r/SNPedia

rs4959039

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 normal
(A;G) 1.4 1.4x higher risk for multiple sclerosis
(G;G) 1.6 1.6x higher risk for multiple sclerosis
ReferenceGRCh38 38.1/141
Chromosome6
Position29989292
is asnp
is mentioned by
dbSNPrs4959039
ebirs4959039
HLIrs4959039
Exacrs4959039
Varsomers4959039
Maprs4959039
PheGenIrs4959039
hapmaprs4959039
1000 genomesrs4959039
hgdprs4959039
ensemblrs4959039
gopubmedrs4959039
geneviewrs4959039
scholarrs4959039
googlers4959039
pharmgkbrs4959039
gwascentralrs4959039
openSNPrs4959039
23andMers4959039
23andMe allrs4959039
SNP Nexus

SNPshotrs4959039
SNPdbers4959039
MSV3drs4959039
GWAS Ctlgrs4959039
GMAF0.2617
Max Magnitude1.6
? (A;A) (A;G) (G;G) 28
rs4959039 is a SNP located within the Class I HLA-G region of chromosome 6.

Independently of the influence of the (nearby) HLA-DRB1*1501 allele, the rs4959039(G) was shown to be associated with increased risk for multiple sclerosis in a study of ~2,300 patients.[PMID 20593013OA-icon.png]