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rs4963

From SNPedia

Orientationplus
Stabilizedplus
Make rs4963(C;C)
Make rs4963(C;G)
Make rs4963(G;G)
ReferenceGRCh38 38.1/141
Chromosome4
Position2915035
GeneADD1
is asnp
is mentioned by
dbSNPrs4963
ebirs4963
HLIrs4963
Exacrs4963
Varsomers4963
Maprs4963
PheGenIrs4963
hapmaprs4963
1000 genomesrs4963
hgdprs4963
ensemblrs4963
gopubmedrs4963
geneviewrs4963
scholarrs4963
googlers4963
pharmgkbrs4963
gwascentralrs4963
openSNPrs4963
23andMers4963
23andMe allrs4963
SNP Nexus

SNPshotrs4963
SNPdbers4963
MSV3drs4963
GWAS Ctlgrs4963
GMAF0.2709
Max Magnitude
? (C;C) (C;G) (G;G) 28
rs4963 is in very tight linkage with rs4961, another ADD1 gene SNP, and thus linked to hypertension.

The rs4963(C) allele is the more common, predicting (the more common) rs4961(G) allele; the rs4963(G) allele is less common, predicting the rs4961(T) - and risk - allele.

See rs4961 for details.


[PMID 19574959OA-icon.png] Novel genetic variants in the alpha-adducin and guanine nucleotide binding protein beta-polypeptide 3 genes and salt sensitivity of blood pressure.


GET Evidence
ADD1-S617C
aa_change Ser617Cys
aa_change_short S617C
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.180517
summary