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rs4970834

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs4970834(C;T)
Make rs4970834(T;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position109272258
GeneCELSR2
is asnp
is mentioned by
dbSNPrs4970834
ebirs4970834
HLIrs4970834
Exacrs4970834
Varsomers4970834
Maprs4970834
PheGenIrs4970834
hapmaprs4970834
1000 genomesrs4970834
hgdprs4970834
ensemblrs4970834
gopubmedrs4970834
geneviewrs4970834
scholarrs4970834
googlers4970834
pharmgkbrs4970834
gwascentralrs4970834
openSNPrs4970834
23andMers4970834
23andMe allrs4970834
SNP Nexus

SNPshotrs4970834
SNPdbers4970834
MSV3drs4970834
GWAS Ctlgrs4970834
GMAF0.1667
Max Magnitude0
? (C;C) (C;T) (T;T) 28
[PMID 18262040OA-icon.png] rs599839 and rs4970834 explain about 1% of the variation in circulating LDL-cholesterol levels. "When we look at this particular genetic variance, of all the cholesterol variation among the population, 1% of it can be attributed to this particular locus," said Sandhu. "This is equivalent to more established genes for LDL regulation, particularly APOE." rs646776 also linked.

[PMID 18979498OA-icon.png] rs599839, rs4970834 and rs17228212 associated with non-HDL cholesterol.


[PMID 19380133] Significant impact of chromosomal locus 1p13.3 on serum LDL cholesterol and on angiographically characterized coronary atherosclerosis


[PMID 20370913OA-icon.png] Genome-wide association analysis of total cholesterol and high-density lipoprotein cholesterol levels using the Framingham heart study data

[PMID 18179892OA-icon.png] Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.

[PMID 19161620OA-icon.png] An open access database of genome-wide association results.

[PMID 19951432OA-icon.png] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.

[PMID 20018038OA-icon.png] Evaluation of genetic risk scores for lipid levels using genome-wide markers in the Framingham Heart Study.

[PMID 20442857OA-icon.png] Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.