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rs498422

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) normal risk for infertility in Chinese men
(A;C) 1.3 1.42x higher risk for infertility in Chinese men
(C;C) 1.4 >1.42x slightly higher risk for infertility in Chinese men
ReferenceGRCh38 38.1/141
Chromosome6
Position32318984
GeneC6orf10
is asnp
is mentioned by
dbSNPrs498422
ebirs498422
HLIrs498422
Exacrs498422
Varsomers498422
Maprs498422
PheGenIrs498422
hapmaprs498422
1000 genomesrs498422
hgdprs498422
ensemblrs498422
gopubmedrs498422
geneviewrs498422
scholarrs498422
googlers498422
pharmgkbrs498422
gwascentralrs498422
openSNPrs498422
23andMers498422
23andMe allrs498422
SNP Nexus

SNPshotrs498422
SNPdbers498422
MSV3drs498422
GWAS Ctlgrs498422
GMAF0.1538
Max Magnitude1.4
rs3129878 is a SNP on chromosome 6, within a gene known as chromosomal open reading frame 10 (C6orf10). It has been associated with slightly (~40%) higher risk for azoospermia (lack of sperm) and thus male infertility in Chinese but not Japanese men.[PMID 22541561OA-icon.png][PMID 23934009]
? (A;A) (A;C) (C;C) 28

[PMID 23934009] HLA-DPB1*04:01 allele is associated with non-obstructive azoospermia in Japanese patients


[PMID 22541561OA-icon.png] A genome-wide association study reveals that variants within the HLA region are associated with risk for nonobstructive azoospermia.