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rs4986782

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 3.5 slow acetylator = higher risk of smoking-induced lung cancer
(A;G) 3.2 slow acetylator = higher risk of smoking-induced lung cancer
(G;G) 0 common in complete genomics
ReferenceGRCh38 38.1/141
Chromosome8
Position18222607
GeneNAT1
is asnp
is mentioned by
dbSNPrs4986782
ebirs4986782
HLIrs4986782
Exacrs4986782
Varsomers4986782
Maprs4986782
PheGenIrs4986782
hapmaprs4986782
1000 genomesrs4986782
hgdprs4986782
ensemblrs4986782
gopubmedrs4986782
geneviewrs4986782
scholarrs4986782
googlers4986782
pharmgkbrs4986782
gwascentralrs4986782
openSNPrs4986782
23andMers4986782
23andMe allrs4986782
SNP Nexus

SNPshotrs4986782
SNPdbers4986782
MSV3drs4986782
GWAS Ctlgrs4986782
GMAF0.006887
Max Magnitude3.5
? (A;A) (A;G) (G;G) 28
[PMID 22010219OA-icon.png] Phenotype of the Most Common "Slow Acetylator" Arylamine N-Acetyltransferase 1 Genetic Variant (NAT1*14B) is Substrate-Dependent

[PMID 16112301OA-icon.png] NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses.

[PMID 16847422OA-icon.png] Genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2) and risk of non-Hodgkin lymphoma.


GET Evidence
NAT1-R187Q
aa_change Arg187Gln
aa_change_short R187Q
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.0078125
summary