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rs5029937

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0
Make rs5029937(G;T)
Make rs5029937(T;T)
ReferenceGRCh38 38.1/141
Chromosome6
Position137874014
GeneTNFAIP3
is asnp
is mentioned by
dbSNPrs5029937
ebirs5029937
HLIrs5029937
Exacrs5029937
Varsomers5029937
Maprs5029937
PheGenIrs5029937
hapmaprs5029937
1000 genomesrs5029937
hgdprs5029937
ensemblrs5029937
gopubmedrs5029937
geneviewrs5029937
scholarrs5029937
googlers5029937
pharmgkbrs5029937
gwascentralrs5029937
openSNPrs5029937
23andMers5029937
23andMe allrs5029937
SNP Nexus

SNPshotrs5029937
SNPdbers5029937
MSV3drs5029937
GWAS Ctlgrs5029937
GMAF0.124
Max Magnitude0
? (G;G) (G;T) (T;T) 28
[PMID 19417005OA-icon.png] rheumatoid arthritis
  • rs6920220 [P= 2.6 x 10(-6), OR 1.22 (1.13-1.33)].
  • rs5029937
  • rs13207033 protective [P= 0.0001, OR 0.86 (0.8-0.93)] perfectly correlated with rs10499194

The combination of the carriage of both risk alleles of rs6920220 and rs5029937 together with the absence of the protective allele of rs13207033 was strongly associated with RA when compared to carriage of none [OR of 1.86 (95% CI) (1.51-2.29)]. This equates to an effect size of 1.50 (95% CI 1.21-1.85)


[PMID 20498205OA-icon.png] Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers

OMIM180300
Desc
Variant
Relatedalso
OMIM612378
Desc
Variant
Relatedalso
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[PMID 19838195OA-icon.png] A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.


[PMID 20444755OA-icon.png] Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment.


[PMID 22328738OA-icon.png] Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.


[PMID 22798268] Rheumatoid arthritis-associated polymorphisms at 6q23 are associated with radiological damage in autoantibody-positive RA.