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rs5128

From SNPedia

Orientationminus
Stabilizedminus
Make rs5128(C;C)
Make rs5128(C;G)
Make rs5128(G;G)
ReferenceGRCh38.p2 38.2/146
Chromosome11
Position116832924
GeneAPOC3
is asnp
is mentioned by
dbSNPrs5128
ebirs5128
HLIrs5128
Exacrs5128
Varsomers5128
Maprs5128
PheGenIrs5128
hapmaprs5128
1000 genomesrs5128
hgdprs5128
ensemblrs5128
gopubmedrs5128
geneviewrs5128
scholarrs5128
googlers5128
pharmgkbrs5128
gwascentralrs5128
openSNPrs5128
23andMers5128
23andMe allrs5128
SNP Nexus

SNPshotrs5128
SNPdbers5128
MSV3drs5128
GWAS Ctlgrs5128
GMAF0.191
Max Magnitude
? (C;C) (C;G) (G;G) 28
rs5128 (C3238G/3238C>G) is a SNP within the 3' UTR of APOC3 (Apolipoprotein C3).

[PMID 19424489OA-icon.png] subjects with GC/GG genotypes and diabetes exhibited sig. higher triglyceride (p=0.004), total cholesterol (p=0.003) and glucose (p=0.016) compared to CC subjects



[PMID 22848358OA-icon.png] Hypercholesterolemia Is Associated with the Apolipoprotein C-III (APOC3) Genotype in Children Receiving HAART: An Eight-Year Retrospective Study


[PMID 17357073OA-icon.png] Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol.


[PMID 18513389OA-icon.png] New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background.


[PMID 18789138OA-icon.png] The APOA5 Trp19 allele is associated with metabolic syndrome via its association with plasma triglycerides.


[PMID 18801202OA-icon.png] Genetic studies on the APOA1-C3-A5 gene cluster in Asian Indians with premature coronary artery disease.


[PMID 19014573OA-icon.png] Application of two machine learning algorithms to genetic association studies in the presence of covariates.


[PMID 19041386OA-icon.png] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.


[PMID 19057464OA-icon.png] Pharmacogenetic association of the APOA1/C3/A4/A5 gene cluster and lipid responses to fenofibrate: the genetics of lipid-lowering drugs and diet network study.


[PMID 19131662OA-icon.png] A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.


[PMID 19263529OA-icon.png] Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach.


[PMID 20406163] Fenofibrate and metabolic syndrome.


GET Evidence
rs5128
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.888176
summary



[PMID 22924697] Interactions between the apolipoprotein a1/c3/a5 haplotypes and alcohol consumption on serum lipid levels.


[PMID 23021345] Gene-diet interactions on plasma lipid levels in the Inuit population.


[PMID 25653052] Dietary patterns interact with APOA1/APOC3 polymorphisms to alter the risk of the metabolic syndrome: the Tehran Lipid and Glucose Study


[PMID 25928461OA-icon.png] Associations of the APOC3 rs5128 polymorphism with plasma APOC3 and lipid levels: a meta-analysis


[PMID 26824674] Interactions of Environmental Factors and APOA1-APOC3-APOA4-APOA5 Gene Cluster Gene Polymorphisms with Metabolic Syndrome.


[PMID 27690381] Association of Apolipoprotein C3 Genetic Polymorphisms with the Risk of Ischemic Stroke in the Northern Chinese Han Population.