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rs526934

From SNPedia

Orientationplus
Stabilizedplus
Make rs526934(A;A)
Make rs526934(A;G)
Make rs526934(G;G)
ReferenceGRCh38 38.1/141
Chromosome11
Position59866020
GeneTCN1
is asnp
is mentioned by
dbSNPrs526934
ebirs526934
HLIrs526934
Exacrs526934
Varsomers526934
Maprs526934
PheGenIrs526934
hapmaprs526934
1000 genomesrs526934
hgdprs526934
ensemblrs526934
gopubmedrs526934
geneviewrs526934
scholarrs526934
googlers526934
pharmgkbrs526934
gwascentralrs526934
openSNPrs526934
23andMers526934
23andMe allrs526934
SNP Nexus

SNPshotrs526934
SNPdbers526934
MSV3drs526934
GWAS Ctlgrs526934
GMAF0.2176
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19303062OA-icon.png]
Trait Folate pathway vitamins
Title Genome-wide Association Study of Vitamin B6, Vitamin B12, Folate, and Homocysteine Blood Concentrations
Risk Allele A
P-val 0.000002
Odds Ratio 27.62 [11.65-43.59] pg/mL increase
Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway. [PMID 19744961OA-icon.png] G allele associated with lower serum Vitamin B12. "The TCN1 rs526934 G variant may reduce transport of cobalamin, resulting in lower plasma vitamin B12 levels."



[PMID 17119116OA-icon.png] Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER case-control study.


[PMID 19064790OA-icon.png] Predictive genomics of cardioembolic stroke.


GET Evidence
rs526934
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.746032
summary