A meta-analysis involving nine studies with 6,968 breast cancer cases and 9,126 controls found just a borderline significant increased risk (of breast cancer) in a recessive model (odds ratio 1.217, CI: 0.958-1.547, p = 0.107).[PMID 20033767]
[PMID 19820421] The Effect of Genetic Polymorphisms of Cyclooxygenase 2 on Acute Pancreatitis in Turkey
[PMID 19755647] Cyclooxygenase-2 polymorphisms, aspirin treatment, and risk for colorectal adenoma recurrence--data from a randomized clinical trial
[PMID 20711808] Polymorphisms in oxidative stress and inflammation pathway genes, low-dose ionizing radiation, and the risk of breast cancer among US radiologic technologists
[PMID 21705955] Cyclooxygenase-2 polymorphisms and pancreatic cancer susceptibility
[PMID 17171651] Cyclooxygenase-2 polymorphisms in Parkinson's disease.
[PMID 17214885] A polymorphism in the 3' untranslated region of the gene encoding prostaglandin endoperoxide synthase 2 is not associated with an increase in breast cancer risk: a nested case-control study.
[PMID 17404026] Lack of association of the cyclooxygenase-2 and inducible nitric oxide synthase gene polymorphism with risk of cervical cancer in Korean population.
[PMID 17999989] Polymorphic variants in PTGS2 and prostate cancer risk: results from two large nested case-control studies.
[PMID 18085997] Pyrosequencing of polymorphisms in the COX-2 gene (PTGS2) with reported clinical relevance.
[PMID 18768181] Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study.
[PMID 18992148] Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.
[PMID 19223558] Polymorphic variation in NFKB1 and other aspirin-related genes and risk of Hodgkin lymphoma.
[PMID 19318492] Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk.
[PMID 19437564] No association between cyclooxygenase-2 and uridine diphosphate glucuronosyltransferase 1A6 genetic polymorphisms and colon cancer risk.
[PMID 19661089] Genetic variation in immune regulation and DNA repair pathways and stomach cancer in China.
[PMID 22464751] SNPs in PTGS2 and LTA predict pain and quality of life in long term lung cancer survivors.
[PMID 23029430] Prognostic role of host cyclooxygenase and cytokine genotypes in a Caucasian cohort of patients with gastric adenocarcinoma.
[PMID 24870748] The Prostaglandin Synthase 2/cyclooxygenase 2 (PTGS2/ COX2) rs5277 Polymorphism Does not Influence Risk of Colorectal Cancer in an Iranian Population
[PMID 26081267] Genetic Variants in Cyclooxygenase-2 Contribute to Post-treatment Pain among Endodontic Patients