|?|| (A;A) (A;G) (G;G) ||28|
| Disease Association
|| A chromosomal aberration involving ROS1 is found in glioblastoma multiform (GBM). An homozygous deletion in chromosome 6q21 results in expression of a GOPC-ROS1 chimeric protein which has a constitutive receptor tyrosine kinase activity.
[PMID 19863298] rs529038, also known as Asp2213Asn, is not associated with coronary artery disease in a Greek case-control study of ~300 patients.
] Identification of four gene variants associated with myocardial infarction.
[PMID 18506375] Association of genetic variants with atherothrombotic cerebral infarction in Japanese individuals with metabolic syndrome.
[PMID 18599554] Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia.
|| not reviewed
|| Insufficiently evaluated not reviewed