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rs5335

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) normal risk
(C;G) 1.19x risk for hypertension
(G;G) >1.19x risk for hypertension
ReferenceGRCh38 38.1/141
Chromosome4
Position147542688
GeneEDNRA
is asnp
is mentioned by
dbSNPrs5335
ebirs5335
HLIrs5335
Exacrs5335
Varsomers5335
Maprs5335
PheGenIrs5335
hapmaprs5335
1000 genomesrs5335
hgdprs5335
ensemblrs5335
gopubmedrs5335
geneviewrs5335
scholarrs5335
googlers5335
pharmgkbrs5335
gwascentralrs5335
openSNPrs5335
23andMers5335
23andMe allrs5335
SNP Nexus

SNPshotrs5335
SNPdbers5335
MSV3drs5335
GWAS Ctlgrs5335
GMAF0.4986
Max Magnitude
? (C;C) (C;G) (G;G) 28
rs5335, a SNP in the EDNRA gene, has been associated with a (slightly) increased risk for hypertension, based on a study of ~1400 Caucasians. The odds ratio per (G) allele is 1.19 (CI: 1.00-1.41, p=0.05).[PMID 18172451]


[PMID 20028935OA-icon.png] EDNRA variants associate with smooth muscle mRNA levels, cell proliferation rates and cystic fibrosis pulmonary disease severity

[PMID 20964792] A role for endothelin receptor type A in migraine without aura susceptibility? A study in Portuguese patients.


[PMID 23206929] Association study of multiple gene polymorphisms with the risk of adult-onset primary open-angle glaucoma in a Mexican population


[PMID 26178354] [Association between genetic polymorphisms of EDNRA gene and high altitude polycythemia in Tibetans at the Qinghai-Tibetan Plateau]