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rs562338

From SNPedia

Orientationminus
Stabilizedminus
Make rs562338(C;C)
Make rs562338(C;T)
Make rs562338(T;T)
ReferenceGRCh38 38.1/141
Chromosome2
Position21065449
is asnp
is mentioned by
dbSNPrs562338
ebirs562338
HLIrs562338
Exacrs562338
Varsomers562338
Maprs562338
PheGenIrs562338
hapmaprs562338
1000 genomesrs562338
hgdprs562338
ensemblrs562338
gopubmedrs562338
geneviewrs562338
scholarrs562338
googlers562338
pharmgkbrs562338
gwascentralrs562338
openSNPrs562338
23andMers562338
23andMe allrs562338
SNP Nexus

SNPshotrs562338
SNPdbers562338
MSV3drs562338
GWAS Ctlgrs562338
GMAF0.2461
Max Magnitude
? (C;C) (C;T) (T;T) 28

Repeatedly associated with elevated lipids according to [PMID 19161620OA-icon.png]

GWAS snp
PMID [PMID 18262040OA-icon.png]
Trait LDL cholesterol
Title LDL-cholesterol concentrations: a genome-wide association study
Risk Allele T
P-val 1.0000000000000001E-9
Odds Ratio 0.04 [0.02-0.06] mmol/L decrease
GWAS snp
PMID [PMID 18193043]
Trait LDL cholesterol
Title Newly identified loci that influence lipid concentrations and risk of coronary artery disease
Risk Allele G
P-val 5.9999999999999998E-22
Odds Ratio 4.89 [NR] mg/dl higher

[PMID 18179892OA-icon.png] Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.

[PMID 18852197OA-icon.png] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.

[PMID 19060910OA-icon.png] Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.

[PMID 21347282OA-icon.png] Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.


GET Evidence
rs562338
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.671875
summary



[PMID 23150898OA-icon.png] Evaluation of seven common lipid associated loci in a large Indian sib pair study


[PMID 23653095OA-icon.png] Positive correlation between variants of lipid metabolism‑related genes and coronary heart disease