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rs56337013

From SNPedia

Clopidogrel (Plavix®)
Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 normal
(C;T) carrier of one CYP2C19*5 allele
(T;T) 3 CYP2C19*5 homozygote
ReferenceGRCh38 38.1/141
Chromosome10
Position94852738
GeneCYP2C19
is asnp
is mentioned by
dbSNPrs56337013
ebirs56337013
HLIrs56337013
Exacrs56337013
Varsomers56337013
Maprs56337013
PheGenIrs56337013
hapmaprs56337013
1000 genomesrs56337013
hgdprs56337013
ensemblrs56337013
gopubmedrs56337013
geneviewrs56337013
scholarrs56337013
googlers56337013
pharmgkbrs56337013
gwascentralrs56337013
openSNPrs56337013
23andMers56337013
23andMe allrs56337013
SNP Nexus

SNPshotrs56337013
SNPdbers56337013
MSV3drs56337013
GWAS Ctlgrs56337013
Max Magnitude3
CPMC Logo.png

This SNP has been recognized by the Coriell Personalized Medicine Collaborative ICOB.
Additional information is available here

The rs56337013(T) allele defines the CYP2C19 variant known as CYP2C19*5.

This variant is quite rare (< 1% of Caucasians or Chinese), and leads to a poor metabolizer phenotype. [PMID 10022751]


[PMID 21247447OA-icon.png] CYP2C19 and ABCB1 gene polymorphisms are differently distributed according to ethnicity in the Brazilian general population

OMIM124020
Desc
Variant0002
Relatedalso
ClinVar
Risk rs56337013(T;T)
Alt rs56337013(T;T)
Reference rs56337013(C;C)
Significance Drug-response
Disease Mephenytoin
Variation info
Gene CYP2C19
CLNDBN Mephenytoin, poor metabolism of
Reversed 0
HGVS NC_000010.10:g.96612495C>T
CLNSRC OMIM Allelic Variant
CLNACC RCV000018396.28,