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rs57081121

From SNPedia

Merged intors4986893
Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) homozygous CYP2C19*3
(A;G) heterozygous CYP2C19*3
(G;G) 0 not a CYP2C19*3 carrier
ReferenceGRCh38 38.1/141
Chromosome10
Position94780653
GeneCYP2C19
is asnp
is mentioned by
dbSNPrs57081121
ebirs57081121
HLIrs57081121
Exacrs57081121
Varsomers57081121
Maprs57081121
PheGenIrs57081121
hapmaprs57081121
1000 genomesrs57081121
hgdprs57081121
ensemblrs57081121
gopubmedrs57081121
geneviewrs57081121
scholarrs57081121
googlers57081121
pharmgkbrs57081121
gwascentralrs57081121
openSNPrs57081121
23andMers57081121
23andMe allrs57081121
SNP Nexus

SNPshotrs57081121
SNPdbers57081121
MSV3drs57081121
GWAS Ctlgrs57081121
StatusMerged into rs4986893
Max Magnitude0
rs57081121(A) is an allele defining the CYP2C19*3 form of this cytochrome p450.[PMID 18521743]

As a nonfunctioning CYP2C19, this variant would be expected to be a poor metabolizer of several commonly prescribed drugs, including anti-ulcer drugs like omeprazole (trade names Losec and Prilosec), esomeprazole (trade name Nexium), and lansoprazole (Prevacid).