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rs5882(A;G)

From SNPedia

Lower risk of dementia and Alzheimer's disease. Higher good cholesterol.
Is agenotype
ofrs5882
GeneCETP
Chromosome16
Position56,982,180
mentionedby
Magnitude2
ReputeGood
Geno Mag Summary
(A;A) 2 Faster aging. Increased risk for Dementia. Less good cholesterol.
(A;G) 2 Lower risk of dementia and Alzheimer's disease. Higher good cholesterol.
(G;G) 2.1 Longer lifespan, 0.28x lower risk of dementia, 0.31x lower risk of Alzheimer's.

One copy of a longevity gene. This seems to raise HDL ("good") cholesterol, and reduce the risk of dementia and Alzheimer's disease. It may slightly increase longevity. It has been particularly studied in Ashkenazi Jews.