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rs5908

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 common in complete genomics
Make rs5908(A;G)
Make rs5908(G;G)
ReferenceGRCh38 38.1/141
Chromosome5
Position75356374
GeneHMGCR
is asnp
is mentioned by
dbSNPrs5908
ebirs5908
HLIrs5908
Exacrs5908
Varsomers5908
Maprs5908
PheGenIrs5908
hapmaprs5908
1000 genomesrs5908
hgdprs5908
ensemblrs5908
gopubmedrs5908
geneviewrs5908
scholarrs5908
googlers5908
pharmgkbrs5908
gwascentralrs5908
openSNPrs5908
23andMers5908
23andMe allrs5908
SNP Nexus

SNPshotrs5908
SNPdbers5908
MSV3drs5908
GWAS Ctlgrs5908
GMAF0.006887
Max Magnitude0
? (A;A) (A;G) (G;G) 28

[PMID 22050757] Functional non-synonymous polymorphisms prediction methods: current approaches and future developments


[PMID 18802019OA-icon.png] Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13.


[PMID 19554360OA-icon.png] The HMG-CoA reductase gene and lipid and lipoprotein levels: the multi-ethnic study of atherosclerosis.


[PMID 20578904] Common variants of HMGCR, CETP, APOAI, ABCB1, CYP3A4, and CYP7A1 genes as predictors of lipid-lowering response to atorvastatin therapy.


GET Evidence
HMGCR-I638V
aa_change Ile638Val
aa_change_short I638V
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.0129206
summary