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rs5934505

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) most common genotype, lower testosterone
Make rs5934505(C;C)
Make rs5934505(C;T)
ReferenceGRCh38 38.1/141
ChromosomeX
Position8945785
is asnp
is mentioned by
dbSNPrs5934505
ebirs5934505
HLIrs5934505
Exacrs5934505
Varsomers5934505
Maprs5934505
PheGenIrs5934505
hapmaprs5934505
1000 genomesrs5934505
hgdprs5934505
ensemblrs5934505
gopubmedrs5934505
geneviewrs5934505
scholarrs5934505
googlers5934505
pharmgkbrs5934505
gwascentralrs5934505
openSNPrs5934505
23andMers5934505
23andMe allrs5934505
SNP Nexus

SNPshotrs5934505
SNPdbers5934505
MSV3drs5934505
GWAS Ctlgrs5934505
GMAF0.2703
Max Magnitude
? (C;C) (C;T) (T;T) 28
[PMID 21998597OA-icon.png] "Genetic determinants of serum testosterone concentrations in men" - The rs5934505 polymorphism near FAM9B on the X chromosome was also associated with testosterone concentrations (p?=?5.6×10(-16)). The mean serum testosterone and calculated free testosterone but not SHBG concentrations were lower in men with T genotype than in those with C genotype for rs5934505.
GWAS snp
PMID [PMID 22936694OA-icon.png]
Trait Androgen levels
Title Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men.
Risk Allele G
P-val 2E-8
Odds Ratio .09 [0.060-0.122] unit increase


[PMID 23258625] Mendelian randomization suggests non-causal associations of testosterone with cardiometabolic risk factors and mortality.


[PMID 26602056] The rs5934505 single nucleotide polymorphism (SNP) is associated with low testosterone and late-onset hypogonadism, but the rs10822184 SNP is associated with overweight and obesity in a Chinese Han population: a case-control study