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rs5945572

From SNPedia

Associated with prostate cancer risk
Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 1.1 Higher prostate cancer risk ?
Make rs5945572(A;G)
Make rs5945572(G;G)
ReferenceGRCh38 38.1/141
ChromosomeX
Position51486831
is asnp
is mentioned by
dbSNPrs5945572
ebirs5945572
HLIrs5945572
Exacrs5945572
Varsomers5945572
Maprs5945572
PheGenIrs5945572
hapmaprs5945572
1000 genomesrs5945572
hgdprs5945572
ensemblrs5945572
gopubmedrs5945572
geneviewrs5945572
scholarrs5945572
googlers5945572
pharmgkbrs5945572
gwascentralrs5945572
openSNPrs5945572
23andMers5945572
23andMe allrs5945572
SNP Nexus

SNPshotrs5945572
SNPdbers5945572
MSV3drs5945572
GWAS Ctlgrs5945572
GMAF0.2382
Max Magnitude1.1
? (A;A) (A;G) (G;G) 28
Associated with prostate cancer [PMID 18264098OA-icon.png][PMID 18774487]
GWAS
SNP rs5945572
PubMedID [PMID 18264098OA-icon.png]
Condition Prostate cancer
Gene NUDT10, NUDT11, LOC340602, GSPT2, MAGED1
Risk Allele A
pValue 4.00E-013
OR 1.23
95% CI 1.16-1.30


[PMID 19549809OA-icon.png] Fine-Mapping and Family-Based Association Analyses of Prostate Cancer Risk Variants at Xp11

OMIM176807
DescPROSTATE CANCER
Variant
Relatedalso
OMIM300704
DescPROSTATE CANCER, HEREDITARY, X-LINKED 2; HPCX2
Variant
Relatedalso

[PMID 19902474] Replication of prostate cancer risk loci on 8q24, 11q13, 17q12, 19q33, and Xp11 in African Americans



[PMID 20651075OA-icon.png] Prostate Cancer Susceptibility Variants Confer Increased Risk of Disease Progression


[PMID 18708398OA-icon.png] Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium.

[PMID 19318432OA-icon.png] Generalizability of associations from prostate cancer genome-wide association studies in multiple populations.

[PMID 19336566OA-icon.png] Replication of the 10q11 and Xp11 prostate cancer risk variants: results from a Utah pedigree-based study.

[PMID 20690139] Meta-analysis of genome-wide and replication association studies on prostate cancer.

[PMID 21071540OA-icon.png] Validation of genome-wide prostate cancer associations in men of African descent.

[PMID 21390317OA-icon.png] Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.


GET Evidence
rs5945572
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.684783
summary



[PMID 23159463] Genetic sequence variants are associated with severity of lower urinary tract symptoms and prostate cancer susceptibility.