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rs5945619

From SNPedia

Orientationplus
Stabilizedplus
Make rs5945619(C;C)
Make rs5945619(C;T)
Make rs5945619(T;T)
ReferenceGRCh38 38.1/141
ChromosomeX
Position51498820
is asnp
is mentioned by
dbSNPrs5945619
ebirs5945619
HLIrs5945619
Exacrs5945619
Varsomers5945619
Maprs5945619
PheGenIrs5945619
hapmaprs5945619
1000 genomesrs5945619
hgdprs5945619
ensemblrs5945619
gopubmedrs5945619
geneviewrs5945619
scholarrs5945619
googlers5945619
pharmgkbrs5945619
gwascentralrs5945619
openSNPrs5945619
23andMers5945619
23andMe allrs5945619
SNP Nexus

SNPshotrs5945619
SNPdbers5945619
MSV3drs5945619
GWAS Ctlgrs5945619
GMAF0.2618
Max Magnitude
? (C;C) (C;T) (T;T) 28

cancer-genetics these snps influence genetic risk for prostate cancer


[PMID 19336566OA-icon.png] Replication of the 10q11 and Xp11 Prostate Cancer Risk Variants: Results from a Utah Pedigree-Based Study.

[PMID 19366831OA-icon.png] Analysis of Recently Identified Prostate Cancer Susceptibility Loci in a Population-based Study: Associations with Family History and Clinical Features

GWAS snp
PMID [PMID 18264097]
Trait Prostate cancer
Title Multiple newly identified loci associated with prostate cancer susceptibility
Risk Allele C
P-val 2.0000000000000001E-9
Odds Ratio 1.19 [1.07-1.31]


[PMID 19549809OA-icon.png] Fine-Mapping and Family-Based Association Analyses of Prostate Cancer Risk Variants at Xp11

OMIM300704
DescPROSTATE CANCER, HEREDITARY, X-LINKED 2; HPCX2
Variant
Relatedalso
[PMID 18708398OA-icon.png] Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium.

[PMID 18794092OA-icon.png] Association of prostate cancer risk variants with clinicopathologic characteristics of the disease.

[PMID 18974127OA-icon.png] Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer.

[PMID 19104501OA-icon.png] Prostate cancer genomics: towards a new understanding.

[PMID 19434657OA-icon.png] Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients.

[PMID 19549807OA-icon.png] Prostate cancer risk associated loci in African Americans.

[PMID 19639606OA-icon.png] Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.

[PMID 20039378OA-icon.png] Estimation of genotype relative risks from pedigree data by retrospective likelihoods.

[PMID 20690139] Meta-analysis of genome-wide and replication association studies on prostate cancer.

[PMID 21071540OA-icon.png] Validation of genome-wide prostate cancer associations in men of African descent.

[PMID 21390317OA-icon.png] Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.

[PMID 21538423OA-icon.png] Early onset prostate cancer has a significant genetic component.


GET Evidence
rs5945619
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.641304
summary