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rs610932

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 1.5 A allele associated with reduced risk of Alzheimer's in Chinese Han population.
(A;C) 1.2
(C;C) 1.1
ReferenceGRCh38 38.1/141
Chromosome11
Position60171834
GeneMS4A6A
is asnp
is mentioned by
dbSNPrs610932
ebirs610932
HLIrs610932
Exacrs610932
Varsomers610932
Maprs610932
PheGenIrs610932
hapmaprs610932
1000 genomesrs610932
hgdprs610932
ensemblrs610932
gopubmedrs610932
geneviewrs610932
scholarrs610932
googlers610932
pharmgkbrs610932
gwascentralrs610932
openSNPrs610932
23andMers610932
23andMe allrs610932
SNP Nexus

SNPshotrs610932
SNPdbers610932
MSV3drs610932
GWAS Ctlgrs610932
GMAF0.4219
Max Magnitude1.5
? (A;A) (A;C) (C;C) 28
Alzheimer's disease associated, based on large 2011 study 10.1038/ng.803
GWAS snp
PMID [PMID 21460840OA-icon.png]
Trait
Title Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
Risk Allele
P-val 2E-14
Odds Ratio 1.1100 [1.09-1.15]

[PMID 19734902OA-icon.png] Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.

[PMID 22382309] The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer's disease.


[PMID 23180304] Genetic risk score predicting accelerated progression from mild cognitive impairment to Alzheimer's disease.


[PMID 23232270] Association of GWAS-linked loci with late-onset Alzheimer's disease in a northern Han Chinese population.


[PMID 25189118] Late-onset Alzheimer's risk variants in memory decline, incident mild cognitive impairment, and Alzheimer's disease


[PMID 26455864] Association of CD33 and MS4A cluster variants with Alzheimer's disease in East Asian Populations