Have questions? Visit https://www.reddit.com/r/SNPedia

rs61764370

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(T;T) 0
Make rs61764370(G;G)
Make rs61764370(G;T)
ReferenceGRCh38 38.1/141
Chromosome12
Position25207290
GeneKRAS
is asnp
is mentioned by
dbSNPrs61764370
ebirs61764370
HLIrs61764370
Exacrs61764370
Varsomers61764370
Maprs61764370
PheGenIrs61764370
hapmaprs61764370
1000 genomesrs61764370
hgdprs61764370
ensemblrs61764370
gopubmedrs61764370
geneviewrs61764370
scholarrs61764370
googlers61764370
pharmgkbrs61764370
gwascentralrs61764370
openSNPrs61764370
23andMers61764370
23andMe allrs61764370
SNP Nexus

SNPshotrs61764370
SNPdbers61764370
MSV3drs61764370
GWAS Ctlgrs61764370
GMAF0.04362
Max Magnitude0
[PMID 21385923OA-icon.png] Contrary to the claims of a test being marketed, a large study (8,500+ patients and >10,000 controls) found no evidence for any association between rs61764370 and any form of ovarian cancer.


[PMID 20676756OA-icon.png] Prevalence of the variant allele rs61764370 T>G in the 3'UTR of KRAS among Dutch BRCA1, BRCA2 and non-BRCA1/BRCA2 breast cancer families


[PMID 21435948OA-icon.png] A 3'-untranslated region KRAS variant and triple-negative breast cancer: a case-control and genetic analysis

This letter in the Lancet challenges the claims of an association with triple-negative breast cancer in [PMID 21435948OA-icon.png]


[PMID 22679560OA-icon.png] KRas-LCS6 polymorphism does not impact on outcomes in ovarian cancer

[PMID 20647319OA-icon.png] A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk.


[PMID 21807336] Association between KRAS rs61764370 and triple-negative breast cancer--a false positive?


[PMID 22003074] KRAS rs61764370 in Epithelial Ovarian Cancer-Letter.


[PMID 22584434OA-icon.png] High Let-7a MicroRNA Levels in KRAS-Mutated Colorectal Carcinomas May Rescue Anti-EGFR Therapy Effects in Patients with Chemotherapy-Refractory Metastatic Disease.


[PMID 23167843OA-icon.png] Let-7 miRNA-binding site polymorphism in the KRAS 3`UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab


[PMID 24282149] Targeted Knock-in of the Polymorphism rs61764370 does not Affect KRAS Expression but Reduces let-7 Levels


[PMID 23010532OA-icon.png] No evidence for genetic association with the let-7 microRNA-binding site or other common KRAS variants in risk of endometriosis.


[PMID 23324806] The LCS6 polymorphism in the binding site of let-7 microRNA to the KRAS 3'-untranslated region: its role in the efficacy of anti-EGFR-based therapy in metastatic colorectal cancer patients.


[PMID 25081901OA-icon.png] A 3'UTR KRAS variant is associated with cisplatin resistance in patients with recurrent and/or metastatic head and neck squamous cell carcinoma


[PMID 25183481OA-icon.png] A let-7 microRNA-Binding Site Polymorphism in KRAS Predicts Improved Outcome in Patients with Metastatic Colorectal Cancer Treated with Salvage Cetuximab/Panitumumab Monotherapy


[PMID 26515332] KRAS polymorphisms are associated with survival of CRC in Chinese population


[PMID 27221928] The rs61764370 Functional Variant in the KRAS Oncogene is Associated with Chronic Myeloid Leukemia Risk in Women.