Have questions? Visit https://www.reddit.com/r/SNPedia

rs6189

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(G;G) 0 common in complete genomics
Make rs6189(A;A)
Make rs6189(A;G)
ReferenceGRCh38 38.1/142
Chromosome5
Position143400774
GeneNR3C1
is asnp
is mentioned by
dbSNPrs6189
ebirs6189
HLIrs6189
Exacrs6189
Varsomers6189
Maprs6189
PheGenIrs6189
hapmaprs6189
1000 genomesrs6189
hgdprs6189
ensemblrs6189
gopubmedrs6189
geneviewrs6189
scholarrs6189
googlers6189
pharmgkbrs6189
gwascentralrs6189
openSNPrs6189
23andMers6189
23andMe allrs6189
SNP Nexus

SNPshotrs6189
SNPdbers6189
MSV3drs6189
GWAS Ctlgrs6189
GMAF0.01331
Max Magnitude0
? (A;A) (A;G) (G;G) 28

[PMID 20440229] Glucocorticoid receptor gene polymorphisms in Italian patients with eating disorders and obesity


[PMID 20547006] FKBP5 and resistant attachment predict cortisol reactivity in infants: Gene-environment interaction


[PMID 21164266] Glucocorticoid resistance


[PMID 22427805OA-icon.png] Glucocorticoid Receptor 1B and 1C mRNA Transcript Alterations in Schizophrenia and Bipolar Disorder, and Their Possible Regulation by GR Gene Variants


[PMID 22507373] Glucocorticoid receptor gene polymorphisms are associated with reduced first-phase glucose-stimulated insulin secretion and disposition index in women, but not in men


[PMID 19673019OA-icon.png] IL-10 and TNF-alpha promoter haplotypes are associated with childhood Crohn's disease location.


[PMID 20712049OA-icon.png] Glucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients.


[PMID 21448414OA-icon.png] Molecular mechanism of glucocorticoid resistance in inflammatory bowel disease.


[PMID 22781842OA-icon.png] Variation in the glucocorticoid receptor gene at rs41423247 moderates the effect of prenatal maternal psychological symptoms on child cortisol reactivity and behavior


[PMID 23055001] Genetic evidence for the association of the hypothalamic-pituitary-adrenal (HPA) axis with ADHD and methylphenidate treatment response.


ClinVar
Risk rs6189(A;A)
Alt rs6189(A;A)
Reference rs6189(G;G)
Significance Pathogenic
Disease Glucocorticoid resistance
Variation info
Gene NR3C1
CLNDBN Glucocorticoid resistance, relative
Reversed 1
HGVS NC_000005.9:g.142780339C>T
CLNSRC OMIM Allelic Variant
CLNACC RCV000017536.30,



[PMID 25644744] Single Nucleotide Polymorphisms in the Non-coding Region of the Glucocorticoid Receptor Gene and Prednisone Response in Childhood Acute Lymphoblastic Leukemia


[PMID 25724472OA-icon.png] Polymorphisms in the glucocorticoid receptor gene and in the glucocorticoid-induced transcript 1 gene are associated with disease activity and response to glucocorticoid bridging therapy in rheumatoid arthritis