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rs622342

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0
(C;C) 2 influences dosage for Parkinson's patients
Make rs622342(A;C)
ReferenceGRCh38 38.1/141
Chromosome6
Position160151834
GeneSLC22A1
is asnp
is mentioned by
dbSNPrs622342
ebirs622342
HLIrs622342
Exacrs622342
Varsomers622342
Maprs622342
PheGenIrs622342
hapmaprs622342
1000 genomesrs622342
hgdprs622342
ensemblrs622342
gopubmedrs622342
geneviewrs622342
scholarrs622342
googlers622342
pharmgkbrs622342
gwascentralrs622342
openSNPrs622342
23andMers622342
23andMe allrs622342
SNP Nexus

SNPshotrs622342
SNPdbers622342
MSV3drs622342
GWAS Ctlgrs622342
GMAF0.2713
Max Magnitude2
? (A;A) (A;C) (C;C) 28

[PMID 19381165] Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus


[PMID 19898263] Interaction between polymorphisms in the OCT1 and MATE1 transporter and metformin response



[PMID 20680652OA-icon.png] OCT1 polymorphism is associated with response and survival time in anti-Parkinsonian drug users


[PMID 21241070] Clinical pharmacokinetics of metformin


GET Evidence
rs622342
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.706349
summary



[PMID 22882994] Pharmacogenomic association between a variant in SLC47A1 gene and therapeutic response to metformin in type 2 diabetes.


[PMID 23612856] Genetic polymorphisms of OCT-1 confer susceptibility to severe progression of primary biliary cirrhosis in Japanese patients.


[PMID 25398212] Genetic polymorphisms of the organic cation transporter 1 gene (SLC22A1) within the Cape Admixed population of South Africa


[PMID 25492374] Influence of SLC22A1 rs622342 genetic polymorphism on metformin response in South Indian type 2 diabetes mellitus patients