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rs6426833

From SNPedia

Orientationplus
Stabilizedplus
Make rs6426833(A;A)
Make rs6426833(A;G)
Make rs6426833(G;G)
ReferenceGRCh38 38.1/141
Chromosome1
Position19845367
is asnp
is mentioned by
dbSNPrs6426833
ebirs6426833
HLIrs6426833
Exacrs6426833
Varsomers6426833
Maprs6426833
PheGenIrs6426833
hapmaprs6426833
1000 genomesrs6426833
hgdprs6426833
ensemblrs6426833
gopubmedrs6426833
geneviewrs6426833
scholarrs6426833
googlers6426833
pharmgkbrs6426833
gwascentralrs6426833
openSNPrs6426833
23andMers6426833
23andMe allrs6426833
SNP Nexus

SNPshotrs6426833
SNPdbers6426833
MSV3drs6426833
GWAS Ctlgrs6426833
GMAF0.4362
Max Magnitude
? (A;A) (A;G) (G;G) 28
A genome-wide association study using DNA samples from 1,052 individuals with ulcerative colitis and preexisting data from 2,571 controls, all of European ancestry, concluded that this SNP and several others were associated with altered risk for the disease.[PMID 19122664OA-icon.png]
OMIM605225
DescINFLAMMATORY BOWEL DISEASE 7; IBD7
Variant
Relatedalso


GWAS snp
PMID [PMID 19915572OA-icon.png]
Trait Ulcerative colitis
Title Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
Risk Allele
P-val 2E-11
Odds Ratio NR NR
GWAS snp
PMID [PMID 20228799OA-icon.png]
Trait Ulcerative colitis
Title Genome-wide association identifies multiple ulcerative colitis susceptibility loci
Risk Allele A
P-val 2E-21
Odds Ratio 1.30 [NR]
GWAS snp
PMID [PMID 21297633OA-icon.png]
Trait
Title Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Risk Allele A
P-val 4E-35
Odds Ratio 1.3000 [1.25-1.35]


[PMID 21304977OA-icon.png] An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.


GET Evidence
rs6426833
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.5625
summary



GWAS snp
PMID [PMID 23128233OA-icon.png]
Trait Ulcerative colitis
Title Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Risk Allele A
P-val 2E-68
Odds Ratio 1.27 [1.221-1.31]