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rs6446482

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in clinvar
Make rs6446482(C;G)
Make rs6446482(G;G)
ReferenceGRCh38 38.1/141
Chromosome4
Position6293966
GeneWFS1
is asnp
is mentioned by
dbSNPrs6446482
ebirs6446482
HLIrs6446482
Exacrs6446482
Varsomers6446482
Maprs6446482
PheGenIrs6446482
hapmaprs6446482
1000 genomesrs6446482
hgdprs6446482
ensemblrs6446482
gopubmedrs6446482
geneviewrs6446482
scholarrs6446482
googlers6446482
pharmgkbrs6446482
gwascentralrs6446482
openSNPrs6446482
23andMers6446482
23andMe allrs6446482
SNP Nexus

SNPshotrs6446482
SNPdbers6446482
MSV3drs6446482
GWAS Ctlgrs6446482
GMAF0.2741
Max Magnitude0
? (C;C) (C;G) (G;G) 28

[PMID 19258739] Association study of the effect of WFS1 polymorphisms on risk of type 2 diabetes in Japanese population

OMIM125853
DescDIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM
Variant
Relatedalso
OMIM606201
DescWFS1 GENE; WFS1
Variant
Relatedalso


OMIM606201
Desc
Variant0021
Relatedalso
OMIM606201
Desc
Variant0022
Relatedalso
[PMID 18040659OA-icon.png] Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations.


[PMID 18060660OA-icon.png] Testing of diabetes-associated WFS1 polymorphisms in the Diabetes Prevention Program.


[PMID 20509872OA-icon.png] Implication of genetic variants near SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, FTO, TCF2, KCNQ1, and WFS1 in type 2 diabetes in a Chinese population.


GET Evidence
rs6446482
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.6875
summary



[PMID 22996131OA-icon.png] Monogenic models: what have the single gene disorders taught us?


ClinVar
Risk rs6446482(G;G)
Alt rs6446482(G;G)
Reference rs6446482(C;C)
Significance Pathogenic
Disease Diabetes mellitus
Variation info
Gene WFS1
CLNDBN Diabetes mellitus, noninsulin-dependent, association with
Reversed 0
HGVS NC_000004.11:g.6295693C>G
CLNSRC OMIM Allelic Variant
CLNACC RCV000004786.7,