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rs6457327

From SNPedia

Orientationplus
Stabilizedplus
Make rs6457327(A;A)
Make rs6457327(A;C)
Make rs6457327(C;C)
ReferenceGRCh38 38.1/141
Chromosome6
Position31106253
is asnp
is mentioned by
dbSNPrs6457327
ebirs6457327
HLIrs6457327
Exacrs6457327
Varsomers6457327
Maprs6457327
PheGenIrs6457327
hapmaprs6457327
1000 genomesrs6457327
hgdprs6457327
ensemblrs6457327
gopubmedrs6457327
geneviewrs6457327
scholarrs6457327
googlers6457327
pharmgkbrs6457327
gwascentralrs6457327
openSNPrs6457327
23andMers6457327
23andMe allrs6457327
SNP Nexus

SNPshotrs6457327
SNPdbers6457327
MSV3drs6457327
GWAS Ctlgrs6457327
GMAF0.3347
Max Magnitude
? (A;A) (A;C) (C;C) 28

news the presence of the G allele was protective against follicular lymphoma, while the presence of the A allele was predictive of an increased risk of developing follicular lymphoma. Dr. Brown said individuals who had the A variant were nearly twice as likely to develop follicular lymphoma.

23andMe blog coverage

GWAS snp
PMID [PMID 19620980OA-icon.png]
Trait Follicular lymphoma
Title Genetics variants at 6p21.33 are associated with susceptibility to follicular lymphoma
Risk Allele C
P-val 5E-11
Odds Ratio 1.69 [1.43-2.00]
GWAS snp
PMID [PMID 20639881OA-icon.png]
Trait Follicular lymphoma
Title Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32
Risk Allele C
P-val 0.000007
Odds Ratio 1.47 [1.27-1.72]

[PMID 21233317OA-icon.png] SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma

OMIM613024
Desc
Variant
Relatedalso


GET Evidence
rs6457327
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.664062
summary