rs6465657
| Influences risk for prostate cancer |
| Orientation | plus |
| Stabilized | plus |
| Make rs6465657(C;C) |
| Make rs6465657(C;T) |
| Make rs6465657(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 98187015 |
| Gene | LMTK2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs6465657 |
| dbSNP (classic) | rs6465657 |
| ClinGen | rs6465657 |
| ebi | rs6465657 |
| HLI | rs6465657 |
| Exac | rs6465657 |
| Gnomad | rs6465657 |
| Varsome | rs6465657 |
| LitVar | rs6465657 |
| Map | rs6465657 |
| PheGenI | rs6465657 |
| Biobank | rs6465657 |
| 1000 genomes | rs6465657 |
| hgdp | rs6465657 |
| ensembl | rs6465657 |
| geneview | rs6465657 |
| scholar | rs6465657 |
| rs6465657 | |
| pharmgkb | rs6465657 |
| gwascentral | rs6465657 |
| openSNP | rs6465657 |
| 23andMe | rs6465657 |
| SNPshot | rs6465657 |
| SNPdbe | rs6465657 |
| MSV3d | rs6465657 |
| GWAS Ctlg | rs6465657 |
| GMAF | 0.2801 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
cancer-genetics these snps influence genetic risk for prostate cancer
- the haplotype rs6983267 rs1016343 rs4242384
- rs7501939
- rs1859962
- rs2660753
- rs9364554
- rs6465657
- rs10993994
- rs7931342
- rs2735839
- rs5945619
- rs10993994
| GWAS | |
|---|---|
| SNP | rs6465657 |
| PubMedID | [PMID 18264097] |
| Condition | Prostate cancer |
| Gene | LMTK2 |
| Risk Allele | C |
| pValue | 1.00E-009 |
| OR | 1.12 |
| 95% CI | 1.05-1.20 |
[PMID 19336566
] Replication of the 10q11 and Xp11 Prostate Cancer Risk Variants: Results from a Utah Pedigree-Based Study.
| GWAS snp | |
|---|---|
| PMID | [PMID 19767753]
|
| Trait | Prostate cancer |
| Title | Identification of seven new prostate cancer susceptibility loci through a genome-wide association study |
| Risk Allele | T |
| P-val | 2E-8 |
| Odds Ratio | NR NR |
[PMID 20569440] Alterations in LMTK2, MSMB and HNF1B gene expression are associated with the development of prostate cancer
[PMID 21820706] Prostate Cancer Risk Alleles and Their Associations With Other Malignancies
[PMID 18708398] Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium.
[PMID 18794092] Association of prostate cancer risk variants with clinicopathologic characteristics of the disease.
[PMID 18974127] Association study of prostate cancer susceptibility variants with risks of invasive ovarian, breast, and colorectal cancer.
[PMID 19104501] Prostate cancer genomics: towards a new understanding.
[PMID 19318432] Generalizability of associations from prostate cancer genome-wide association studies in multiple populations.
[PMID 19366831] Analysis of recently identified prostate cancer susceptibility loci in a population-based study: associations with family history and clinical features.
[PMID 19434657] Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients.
[PMID 19549807] Prostate cancer risk associated loci in African Americans.
[PMID 19639606] Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.
[PMID 20039378] Estimation of genotype relative risks from pedigree data by retrospective likelihoods.
[PMID 20450899] Individual and cumulative association of prostate cancer susceptibility variants with clinicopathologic characteristics of the disease.
[PMID 21390317] Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.
[PMID 21538423] Early onset prostate cancer has a significant genetic component.
[PMID 24411283] Prostate Cancer (PCa) Risk Variants and Risk of Fatal PCa in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
