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rs6474413

From SNPedia

Orientationplus
Stabilizedplus
Make rs6474413(C;C)
Make rs6474413(C;T)
Make rs6474413(T;T)
ReferenceGRCh38 38.1/141
Chromosome8
Position42695921
GeneCHRNB3
is asnp
is mentioned by
dbSNPrs6474413
ebirs6474413
HLIrs6474413
Exacrs6474413
Varsomers6474413
Maprs6474413
PheGenIrs6474413
hapmaprs6474413
1000 genomesrs6474413
hgdprs6474413
ensemblrs6474413
gopubmedrs6474413
geneviewrs6474413
scholarrs6474413
googlers6474413
pharmgkbrs6474413
gwascentralrs6474413
openSNPrs6474413
23andMers6474413
23andMe allrs6474413
SNP Nexus

SNPshotrs6474413
SNPdbers6474413
MSV3drs6474413
GWAS Ctlgrs6474413
GMAF0.343
Max Magnitude
? (C;C) (C;T) (T;T) 28
rs6474413 increases susceptibility to Substance dependence, Nicotine 1.35 times for carriers of the T allele [PMID 17135278OA-icon.png]


[PMID 19482438] Association of genes coding for the alpha-4, alpha-5, beta-2 and beta-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence


[PMID 17158188OA-icon.png] Novel genes identified in a high-density genome wide association study for nicotine dependence.


[PMID 18565990OA-icon.png] Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence.


[PMID 18571741OA-icon.png] Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research.


[PMID 18704094OA-icon.png] Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample.


[PMID 19029397OA-icon.png] Nicotinic receptor gene variants influence susceptibility to heavy smoking.


[PMID 19184766OA-icon.png] A testable prognostic model of nicotine dependence.