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rs6494223

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) normal
(C;T) in ALZ patients, increased risk of delusions
(T;T) in ALZ patients, increased risk of delusions
ReferenceGRCh38 38.1/141
Chromosome15
Position32104256
GeneCHRNA7
is asnp
is mentioned by
dbSNPrs6494223
ebirs6494223
HLIrs6494223
Exacrs6494223
Varsomers6494223
Maprs6494223
PheGenIrs6494223
hapmaprs6494223
1000 genomesrs6494223
hgdprs6494223
ensemblrs6494223
gopubmedrs6494223
geneviewrs6494223
scholarrs6494223
googlers6494223
pharmgkbrs6494223
gwascentralrs6494223
openSNPrs6494223
23andMers6494223
23andMe allrs6494223
SNP Nexus

SNPshotrs6494223
SNPdbers6494223
MSV3drs6494223
GWAS Ctlgrs6494223
GMAF0.4578
Max Magnitude
? (C;C) (C;T) (T;T) 28

A significant association between delusions and the rs6494223(T) allele (odds ratio 1.63, CI: 1.22-2.17, p = 0.014, ) was found in a cohort of Alzheimer's disease patients in Northern Ireland.[PMID 18696274]


[PMID 20463630] Evidence for association of the non-duplicated region of CHRNA7 gene with bipolar disorder but not with Schizophrenia


[PMID 21550667] CHRNA7 haplotypes are associated with impaired attention in euthymic bipolar disorder.


[PMID 25054019OA-icon.png] Meta-analyses of 10 polymorphisms associated with the risk of schizophrenia


[PMID 24951635] Effect of APOE and CHRNA7 genotypes on the cognitive response to cholinesterase inhibitor treatment at different stages of Alzheimer's disease