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rs659366

From SNPedia

Orientationplus
Stabilizedplus
Make rs659366(C;C)
Make rs659366(C;T)
Make rs659366(T;T)
ReferenceGRCh38 38.1/141
Chromosome11
Position73983709
GeneUCP2
is asnp
is mentioned by
dbSNPrs659366
ebirs659366
HLIrs659366
Exacrs659366
Varsomers659366
Maprs659366
PheGenIrs659366
hapmaprs659366
1000 genomesrs659366
hgdprs659366
ensemblrs659366
gopubmedrs659366
geneviewrs659366
scholarrs659366
googlers659366
pharmgkbrs659366
gwascentralrs659366
openSNPrs659366
23andMers659366
23andMe allrs659366
SNP Nexus

SNPshotrs659366
SNPdbers659366
MSV3drs659366
GWAS Ctlgrs659366
GMAF0.4155
Max Magnitude
? (C;C) (C;T) (T;T) 28

[PMID 19387457] Association of UCP2 -866 G/A polymorphism with chronic inflammatory diseases

OMIM601693
DescUNCOUPLING PROTEIN 2; UCP2
Variant
Relatedalso
[PMID 19769793OA-icon.png] Variation in the UCP2 and UCP3 genes associates with abdominal obesity and serum lipids: The Finnish Diabetes Prevention Study
OMIM601693
Desc
Variant0001
Relatedalso


[PMID 21883184] Polymorphisms of the UCP2 gene are associated with body fat distribution and risk of abdominal obesity in Spanish population


[PMID 22241057OA-icon.png] Variation in The Uncoupling Protein 2 and 3 Genes and Human Performance

[PMID 16046815OA-icon.png] Data-mining analysis suggests an epigenetic pathogenesis for type 2 diabetes.

[PMID 17570749OA-icon.png] Genetic prediction of future type 2 diabetes.

[PMID 17701054] Interaction between the UCP2-866G/A, mtDNA 10398G/A and PGC1alpha p.Thr394Thr and p.Gly482Ser polymorphisms in type 2 diabetes susceptibility in North Indian population.

[PMID 17870627] Association between obesity and insulin resistance with UCP2-UCP3 gene variants in Spanish children and adolescents.

[PMID 19406964OA-icon.png] Association of genetic variants with chronic kidney disease in Japanese individuals.

[PMID 19681913] Polymorphisms of the UCP2 gene are associated with proliferative diabetic retinopathy in patients with diabetes mellitus.

[PMID 20145583OA-icon.png] Interaction between the UCP2 -866 G>A polymorphism, diabetes, and beta-blocker use among patients with acute coronary syndromes.

[PMID 20359253] Effect of the common -866G/A polymorphism of the uncoupling protein 2 gene on weight loss and body composition under sibutramine therapy in an obese Taiwanese population.

[PMID 22349573] The frequent UCP2 -866G>A polymorphism protects against insulin resistance and is associated with obesity: a study of obesity and related metabolic traits among 17 636 Danes.


[PMID 22533685OA-icon.png] Uncoupling protein 2 gene polymorphisms are associated with obesity


[PMID 23639961] Uncoupling protein 2 -866G/A and uncoupling protein 3 -55C/T polymorphisms in young South African Indian coronary artery disease patients


[PMID 23826253OA-icon.png] Gene Polymorphisms of ADIPOQ +45T>G, UCP2 -866G>A, and FABP2 Ala54Thr on the Risk of Colorectal Cancer: A Matched Case-Control Study


[PMID 25396419OA-icon.png] Investigation of Variants in UCP2 in Chinese Type 2 Diabetes and Diabetic Retinopathy


ClinVar
Risk rs659366(T;T)
Alt rs659366(T;T)
Reference rs659366(C;C)
Significance Other
Disease Body mass index quantitative trait locus 4
Variation info
Gene UCP2
CLNDBN Body mass index quantitative trait locus 4
Reversed 0
HGVS NC_000011.9:g.73694754C>T
CLNSRC OMIM Allelic Variant
CLNACC RCV000023142.3,



[PMID 26402942] [The study of the association of polymorphism rs659366 gene UCP2 c obesity and type 2 diabetes among residents of the Moscow Region]


[PMID 27615599] Interactions between UCP2 SNPs and telomere length exist in the absence of diabetes or pre-diabetes.