Have questions? Visit https://www.reddit.com/r/SNPedia

rs6656401

From SNPedia

Orientationplus
Stabilizedplus
Make rs6656401(A;A)
Make rs6656401(A;G)
Make rs6656401(G;G)
ReferenceGRCh38 38.1/141
Chromosome1
Position207518704
GeneCR1
is asnp
is mentioned by
dbSNPrs6656401
ebirs6656401
HLIrs6656401
Exacrs6656401
Varsomers6656401
Maprs6656401
PheGenIrs6656401
hapmaprs6656401
1000 genomesrs6656401
hgdprs6656401
ensemblrs6656401
gopubmedrs6656401
geneviewrs6656401
scholarrs6656401
googlers6656401
pharmgkbrs6656401
gwascentralrs6656401
openSNPrs6656401
23andMers6656401
23andMe allrs6656401
SNP Nexus

SNPshotrs6656401
SNPdbers6656401
MSV3drs6656401
GWAS Ctlgrs6656401
GMAF0.0877
Max Magnitude
? (A;A) (A;G) (G;G) 28

relevant to Alzheimer's disease, late-onset (IGAP)


[PMID 19734903] Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease


[PMID 20558149] Complement receptor 1 polymorphisms and risk of late onset Alzheimer's disease

OMIM104300
Desc
Variant
Relatedalso
[PMID 21912625OA-icon.png] An exploratory study on CLU, CR1 and PICALM and Parkinson disease


[PMID 22216291OA-icon.png] Association between IgM Anti-Herpes Simplex Virus and Plasma Amyloid-Beta Levels


[PMID 22262751OA-icon.png] Genetic variation at CR1 increases risk of cerebral amyloid angiopathy.

[PMID 20739100OA-icon.png] Genetic variations in the CLU and PICALM genes are associated with cognitive function in the oldest old.

[PMID 21347408OA-icon.png] Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease.

[PMID 21358043] PICALM and CR1 variants are not associated with sporadic Alzheimer's disease in Chinese patients.

[PMID 21391232OA-icon.png] CR1 is associated with amyloid plaque burden and age-related cognitive decline.

[PMID 21726919] CR1 genotype is associated with entorhinal cortex volume in young healthy adults.

[PMID 22015308] Polymorphisms of CR1, CLU and PICALM confer susceptibility of Alzheimer's disease in a southern Chinese population.

[PMID 22244847] Alzheimer's disease risk factor complement receptor 1 is associated with depression.

[PMID 22343410OA-icon.png] A coding variant in CR1 interacts with APOE-epsilon4 to influence cognitive decline.


[PMID 22960360] Association of the CR1 polymorphism with late-onset Alzheimer's disease in Chinese Han populations: A meta-analysis


[PMID 23650005] Lack of association of CR1, PICALM and CLU gene polymorphisms with Alzheimer disease in a Polish population

GWAS snp
PMID [PMID 24162737OA-icon.png]
Trait Alzheimer's disease (late onset)
Title Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Risk Allele A
P-val 6E-24
Odds Ratio 1.18 [1.14-1.22]


[PMID 24878768] An Updated Analysis with 85,939 Samples Confirms the Association Between CR1 rs6656401 Polymorphism and Alzheimer's Disease


[PMID 26680604] Polygenic Analysis of Late-Onset Alzheimer's Disease from Mainland China.