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rs6684865

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 1.5x risk of rheumatoid arthritis
(A;G) 1.2x risk of rheumatoid arthritis
(G;G) normal
ReferenceGRCh38 38.1/141
Chromosome1
Position2614790
GeneMMEL1
is asnp
is mentioned by
dbSNPrs6684865
ebirs6684865
HLIrs6684865
Exacrs6684865
Varsomers6684865
Maprs6684865
PheGenIrs6684865
hapmaprs6684865
1000 genomesrs6684865
hgdprs6684865
ensemblrs6684865
gopubmedrs6684865
geneviewrs6684865
scholarrs6684865
googlers6684865
pharmgkbrs6684865
gwascentralrs6684865
openSNPrs6684865
23andMers6684865
23andMe allrs6684865
SNP Nexus

SNPshotrs6684865
SNPdbers6684865
MSV3drs6684865
GWAS Ctlgrs6684865
GMAF0.4178
Max Magnitude0
? (A;A) (A;G) (G;G) 28
rs6684865 has been reported in a large study to be associated with rheumatoid arthritis.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.27 (CI 1.02-1.56), and for homozygotes, 1.54 (CI 1.25-1.90). [PMID 17554300OA-icon.png]


[PMID 20187130] Evidence of epistasis between TNFRSF14 and TNFRSF6B polymorphisms in patients with rheumatoid arthritis


[PMID 20962851] Members 6B and 14 of the TNF receptor superfamily in multiple sclerosis predisposition


[PMID 18794857OA-icon.png] Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.


[PMID 20017963OA-icon.png] Representation of genetic association via attributable familial relative risks in order to identify polymorphisms functionally relevant to rheumatoid arthritis.


[PMID 20439292] Genetic variants in the prediction of rheumatoid arthritis.