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rs671(A;G)

From SNPedia

Asian Flush; worse hangovers; increased risk of esophageal cancer; East Asian ancestry; Disulfiram probably not effective for alcoholism.
Is agenotype
ofrs671
GeneALDH2
Chromosome12
Position111,803,962
mentionedby
Magnitude3.5
ReputeBad
Geno Mag Summary
(A;A) 4 Asian Flusher; increased risk of esophageal cancer; East Asian ancestry; Disulfiram not effective for alcoholism.
(A;G) 3.5 Asian Flush; worse hangovers; increased risk of esophageal cancer; East Asian ancestry; Disulfiram probably not effective for alcoholism.
(G;G) 2 Alcohol Flush: Normal, doesn't flush. Normal hangovers. Normal risk of Alcoholism. Normal risk of Esophageal Cancer. Disulfiram is effective for alcoholism.

People with this genotype will experience the asian flush, a redness in the face when drinking alcohol. They can only break down acetaldehyde at half the normal speed, a toxic byproduct of alcohol and cigarette smoke. As a result, you are likely to have increased odds of esophageal cancer, especially if you drink or smoke. It also causes worse hangovers. On the bright side, that makes you less likely to become an alcoholic. If you become an alcoholic anyway, disulfiram (Antabuse) probably won't be an effective treatment.