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rs673548

From SNPedia

Orientationplus
Stabilizedplus
Make rs673548(A;A)
Make rs673548(A;G)
Make rs673548(G;G)
ReferenceGRCh38 38.1/141
Chromosome2
Position21014672
GeneAPOB
is asnp
is mentioned by
dbSNPrs673548
ebirs673548
HLIrs673548
Exacrs673548
Varsomers673548
Maprs673548
PheGenIrs673548
hapmaprs673548
1000 genomesrs673548
hgdprs673548
ensemblrs673548
gopubmedrs673548
geneviewrs673548
scholarrs673548
googlers673548
pharmgkbrs673548
gwascentralrs673548
openSNPrs673548
23andMers673548
23andMe allrs673548
SNP Nexus

SNPshotrs673548
SNPdbers673548
MSV3drs673548
GWAS Ctlgrs673548
GMAF0.3485
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19060910OA-icon.png]
Trait Other metabolic traits
Title Genome-wide association analysis of metabolic traits in a birth cohort from a founder population
Risk Allele A
P-val 2E-8
Odds Ratio 0.08 [0.05-0.11] mmol/l decrease


GWAS snp
PMID [PMID 22399527OA-icon.png]
Trait
Title Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
Risk Allele G
P-val 1E-10
Odds Ratio 0.1100 None

[PMID 18296645OA-icon.png] Polymorphisms of genes in the lipid metabolism pathway and risk of biliary tract cancers and stones: a population-based case-control study in Shanghai, China.

[PMID 19060911OA-icon.png] Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

[PMID 19474294OA-icon.png] Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.

[PMID 19936222OA-icon.png] Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.

[PMID 20502693OA-icon.png] Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.


GET Evidence
rs673548
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.242188
summary



GWAS snp
PMID [PMID 22916037OA-icon.png]
Trait Metabolite levels
Title Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
Risk Allele
P-val 1E-13
Odds Ratio NR NR