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rs6782400

From SNPedia

Orientationplus
Stabilizedplus
Make rs6782400(A;A)
Make rs6782400(A;C)
Make rs6782400(C;C)
ReferenceGRCh38 38.1/141
Chromosome3
Position142576526
GeneATR
is asnp
is mentioned by
dbSNPrs6782400
ebirs6782400
HLIrs6782400
Exacrs6782400
Varsomers6782400
Maprs6782400
PheGenIrs6782400
hapmaprs6782400
1000 genomesrs6782400
hgdprs6782400
ensemblrs6782400
gopubmedrs6782400
geneviewrs6782400
scholarrs6782400
googlers6782400
pharmgkbrs6782400
gwascentralrs6782400
openSNPrs6782400
23andMers6782400
23andMe allrs6782400
SNP Nexus

SNPshotrs6782400
SNPdbers6782400
MSV3drs6782400
GWAS Ctlgrs6782400
GMAF0.3811
Max Magnitude
? (A;A) (A;C) (C;C) 28

[PMID 18451257] rs8178085 and rs12334811 with approaching dose-dependent effect on lung cancer predisposition, subjects carrying two to four risk genotypes were associated with a 43% decreased lung cancer risk compared with subjects carrying zero to one risk genotypes (adjusted odds ratio, 0.53; 95% confidence interval, 0.35-0.80).

Moreover, the decreased risk associated with the combined genotypes of rs8178085 and rs12334811 was slightly more pronounced in nonsmokers and in carriers with ataxia-telangiectasia mutated rs228591 variant allele or ataxia-telangiectasia and Rad3-related rs6782400 wild-type homozygous genotype.